The main activity of ISIM is the organization of the Biennial International Congress of Internal Medicine.
The last few congresses took place in:

23rd WCIM - Manila 1996

24th WCIM - Lima 1998

25th WCIM - Cancun 2000

26th WCIM - Kyoto 2002

27th WCIM - Granada 2004

28th WCIM - Taipei 2006

29th WCIM - Buenos Aires and Melbourne 2008

30th WCIM - Australia 2010

31st WCIM - Chile and Seoul 2012

32nd WCIM - Korea 2014

33rd WCIM - Bali 2016

34th WCIM - Cape Town 2018